Soma size and Cav1.3 channel expression in vulnerable and resistant motoneuron populations of the SOD1G93A mouse model of ALS

@inproceedings{Shoenfeld2014SomaSA,
  title={Soma size and Cav1.3 channel expression in vulnerable and resistant motoneuron populations of the SOD1G93A mouse model of ALS},
  author={Liza R. Shoenfeld and Ruth E. Westenbroek and Erika Fisher and Katharina A. Quinlan and Vicki M Tysseling and Randall K. Powers and C. J. Heckman and Marc D. Binder},
  booktitle={Physiological reports},
  year={2014}
}
Although the loss of motoneurons is an undisputed feature of amyotrophic lateral sclerosis (ALS) in man and in its animal models (SOD1 mutant mice), how the disease affects the size and excitability of motoneurons prior to their degeneration is not well understood. This study was designed to test the hypothesis that motoneurons in mutant SOD1(G93A) mice… CONTINUE READING