Som1, a third component of the yeast mitochondrial inner membrane peptidase complex that contains Imp1 and Imp2

@article{Jan2000Som1AT,
  title={Som1, a third component of the yeast mitochondrial inner membrane peptidase complex that contains Imp1 and Imp2},
  author={P Jan and Karlheinz Esser and Elke Pratje and Georg Michaelis},
  journal={Molecular and General Genetics MGG},
  year={2000},
  volume={263},
  pages={483-491}
}
The mitochondrial inner membrane peptidase Imp is required for proteolytic processing of the mitochondrially encoded protein Cox2, the nucleus-encoded Cyt b2, Mcr1, and Cyt c1, and possibly other proteins, during their transport across the mitochondrial membranes. The peptidase contains two catalytic subunits, Imp1 and Imp2. The small protein Som1 was previously shown to affect the function of Imp1, but the precise role of Som1 remained unknown. Using mutants deleted for IMP1, IMP2 and SOM1, we… CONTINUE READING
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