Solving the chemical master equation by a fast adaptive finite state projection based on the stochastic simulation algorithm.

@article{Sidje2015SolvingTC,
  title={Solving the chemical master equation by a fast adaptive finite state projection based on the stochastic simulation algorithm.},
  author={Roger B. Sidje and Huy D. Vo},
  journal={Mathematical biosciences},
  year={2015},
  volume={269},
  pages={10-6}
}
The mathematical framework of the chemical master equation (CME) uses a Markov chain to model the biochemical reactions that are taking place within a biological cell. Computing the transient probability distribution of this Markov chain allows us to track the composition of molecules inside the cell over time, with important practical applications in a number of areas such as molecular biology or medicine. However the CME is typically difficult to solve, since the state space involved can be… CONTINUE READING