Solvent related colour vision loss: an indicator of neural damage?

  title={Solvent related colour vision loss: an indicator of neural damage?},
  author={Donna Mergler and L. M. Buddy Blain and Jos{\'e}e Lagac{\'e}},
  journal={International Archives of Occupational and Environmental Health},
SummaryPrevious studies have related colour vision loss to solvent exposure, raising the question as to its use as an indicator of solvent-related neurotoxic alterations. However, colour vision loss can likewise result from ocular damage. In the present study chromatic discrimination capacity and ocular integrity were examined among 23 workers of a paint manufacture plant exposed to solvent mixtures. Using industrial hygiene data, the workers were classified according to their exposure level… Expand
Chromal focus of acquired chromatic discrimination loss and solvent exposure among printshop workers.
The findings suggest that the type of dyschromatopsia, reflecting the gravity of neural alterations, may be a function of exposure level and/or the ophthalmotoxic properties of the particular solvents used. Expand
Assessing color vision loss among solvent-exposed workers.
The findings of this study indicate that the D-15-d is an adequate instrument for field study batteries, however, the Farnsworth-Munsell 100 Hue (FM-100) should be used for more detailed assessment. Expand
Color vision impairment in workers exposed to neurotoxic chemicals.
Results show that color vision testing should be included in the evaluation of early neurotoxicity of chemicals in exposed workers, and the D-15 d would be useful in the surveillance of workers exposed to solvents and other chemicals toxic to the visual system. Expand
Long-Term Occupational Exposure to Organic Solvents Affects Color Vision, Contrast Sensitivity and Visual Fields
Extensive and diffuse visual changes were found in a group of gas station workers, suggesting that specific occupational limits should be created. Expand
Psychophysical Evaluation of Achromatic and Chromatic Vision of Workers Chronically Exposed to Organic Solvents
Spatial contrast sensitivities of exposed workers were lower than the control at spatial frequencies of 20 and 30 cpd whilst the temporal contrast sensitivity was preserved. Expand
Effects of high doses of toluene on color vision.
Acute exposure to toluene did not cause impairment of color vision, but color vision of the printshop workers tested before cleaning was slightly impaired (statistically not significant) when compared with unexposed subjects. Expand
Impaired colour discrimination among workers exposed to styrene: relevance of a urinary metabolite.
It is suggested that exposure to moderate styrene concentrations can lead to impairment of colour vision, and that there is a significant correlation with the urinary metabolite of styrene. Expand
Acquired Color Vision Defects and Hexane Exposure: A Study of San Francisco Bay Area Automotive Mechanics.
Cumulative exposures to hexane and nonhexane solvents in the highest exposure categories were associated with elevated prevalence ratios for color vision defects in younger participants, and acetone may potentiate the neurotoxicity of n-hexane. Expand
Blue-yellow deficiency in workers exposed to low concentrations of organic solvents
There is further evidence that even mixtures of organic solvents at concentrations below the threshold-limit values may impair color vision. Expand
Exposure to Organic Solvents Used in Dry Cleaning Reduces Low and High Level Visual Function
Exposure to occupational levels of organic solvents is associated with neurotoxicity which is in turn associated with both low level deficits and high level visual deficits such as the perception of global form and motion, but not visual search performance, which indicates that the deficits in visual function are unlikely to be due to changes in general cognitive performance. Expand


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The Desaturated D-15, Standard D-15 and H-16 Panels were used to investigate the colour discrimination of subjects manifesting senile macular degeneration, the effect of illuminance on discriminationExpand
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One hundred and twenty subjects with normal colour vision were examined to investigate the effect of age on performance on the Panel D-15 and the Desaturated D-15. Using the total colour differenceExpand
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Senile macular degeneration and cataract were found to be the commonest causes of visual impairment in the elderly and visually impaired persons were clearly more dependent on home help as compared with the elderly population in general. Expand
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