Solvent effects on alkaline hydrolysis of N-benzylphthalimide in mixed water-acetonitrile and mixed water-N , N-dimethylformamide

@inproceedings{Ye2012SolventEO,
  title={Solvent effects on alkaline hydrolysis of N-benzylphthalimide in mixed water-acetonitrile and mixed water-N , N-dimethylformamide},
  author={Cheong May Ye and Azhar Ariffin and Mohammad Niyaz Khan},
  year={2012}
}
reaction mechanism similar to that for reactions of OHwith phthalimide and its N-alkylphthalimides. The rate of hydrolysis reveals an insignificant contribution of water-catalysed cleavage of NBPT compared with its hydroxide ion catalysed reaction. The observed pseudo first-order rate constant, kobs• for alkaline hydrolysis of NBPT decreases wi th increase in the content of organic cosolvents (up to 70%, vlv) in mixed water-CH3CN and water-DMF solvents.