Solvent effects in thermodynamically controlled multicomponent nanocage syntheses.

@article{Liu2006SolventEI,
  title={Solvent effects in thermodynamically controlled multicomponent nanocage syntheses.},
  author={Xuejun Liu and Ralf Warmuth},
  journal={Journal of the American Chemical Society},
  year={2006},
  volume={128 43},
  pages={14120-7}
}
The solvent effects on the condensation reaction between tetraformylcavitand 2 and ethylene-1,2-diamine 3 are reported. Earlier, it was found that the trifluoroacetic acid-catalyzed condensation of 2 and 2 equiv of 3 in CHCl(3) provides in 82% yield an octahedral nanocage 1 composed of 6 cavitands that are linked together by 12 -CH=N-CH(2)CH(2)-N=CH- linker groups (Liu, X.; Liu, Y.; Li, G.; Warmuth, R. Angew. Chem., Int. Ed. 2006, 45, 901). In tetrahydrofuran, the same reactants yield a… CONTINUE READING