Solvent‐induced organization: A physical model of folding myoglobin

@article{Callaway1994SolventinducedOA,
  title={Solvent‐induced organization: A physical model of folding myoglobin},
  author={David J. E. Callaway},
  journal={Proteins: Structure},
  year={1994},
  volume={20}
}
The essential features of the in vitro refolding of myoglobin are expressed in a solvable physical model. Alpha helices are taken as the fundamental collective coordinates of the system, while the refolding is assumed to be mainly driven by solvent‐induced hydrophobic forces. A quantitative model of these forces is developed and compared with experimental and theoretical results. The model is then tested by being employed in a simulation scheme designed to mimic solvent effects. Realistic… 

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