# Solvent‐induced organization: A physical model of folding myoglobin

@article{Callaway1994SolventinducedOA,
title={Solvent‐induced organization: A physical model of folding myoglobin},
author={David J. E. Callaway},
journal={Proteins: Structure},
year={1994},
volume={20}
}
The essential features of the in vitro refolding of myoglobin are expressed in a solvable physical model. Alpha helices are taken as the fundamental collective coordinates of the system, while the refolding is assumed to be mainly driven by solvent‐induced hydrophobic forces. A quantitative model of these forces is developed and compared with experimental and theoretical results. The model is then tested by being employed in a simulation scheme designed to mimic solvent effects. Realistic…
15 Citations
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