Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I

@article{Bibow2017SolutionSO,
  title={Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I},
  author={Stefan Bibow and Yevhen Polyhach and C{\'e}dric Eichmann and Celestine N. Chi and Julia Kowal and Stefan Albiez and R A Mcleod and Henning Stahlberg and Gunnar Jeschke and Peter G{\"u}ntert and Roland Riek},
  journal={Nature Structural \&Molecular Biology},
  year={2017},
  volume={24},
  pages={187-193}
}
High-density lipoprotein (HDL) particles are cholesterol and lipid transport containers. Mature HDL particles destined for the liver develop through the formation of intermediate discoidal HDL particles, which are the primary acceptors for cholesterol. Here we present the three-dimensional structure of reconstituted discoidal HDL (rdHDL) particles, using a shortened construct of human apolipoprotein A-I, determined from a combination of nuclear magnetic resonance (NMR), electron paramagnetic… 
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