Solution structure of a zinc-finger domain that binds to poly-ADP-ribose.


Poly-ADP-ribosylation is a unique post-translational modification that controls various nuclear events such as repair of DNA single-strand breaks. Recently, the protein containing the poly-ADP-ribose (pADPr)-binding zinc-finger (PBZ) domain was shown to be a novel AP endonuclease and involved in a cell cycle checkpoint. Here, we determined the three… (More)
DOI: 10.1111/j.1365-2443.2009.01369.x


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