Solution structure of BmP01 from the venom of scorpion Buthus martensii Karsch.

@article{Wu2000SolutionSO,
  title={Solution structure of BmP01 from the venom of scorpion Buthus martensii Karsch.},
  author={G. Wu and Y. Li and D. Wei and F. He and S. Jiang and Guoyuan Hu and Houming Wu},
  journal={Biochemical and biophysical research communications},
  year={2000},
  volume={276 3},
  pages={
          1148-54
        }
}
  • G. Wu, Y. Li, +4 authors Houming Wu
  • Published 2000
  • Chemistry, Medicine
  • Biochemical and biophysical research communications
  • From the venom of scorpion Buthus martensii Karsch,a short peptide (BmP01, 29 amino acid residues) was isolated and characterized as previously reported (Lebren, R. R., et al. (1997) Eur. J. Biochem. 245, 457-464). It was shown to reduce 33% outward K(+) channel (hippocampal neurons) currents at 10 microM. The solution structure of BmP01 was determined by 2D (1)H NMR spectroscopy. The NOEs, coupling constants, and H-D exchange obtained from NMR spectroscopy were used in structural calculations… CONTINUE READING
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