Solution structure of (Cd2+)1-calbindin D9k reveals details of the stepwise structural changes along the Apo-->(Ca2+)II1-->(Ca2+)I,II2 binding pathway.

@article{Akke1995SolutionSO,
  title={Solution structure of (Cd2+)1-calbindin D9k reveals details of the stepwise structural changes along the Apo-->(Ca2+)II1-->(Ca2+)I,II2 binding pathway.},
  author={M. Akke and S. Fors{\'e}n and W. Chazin},
  journal={Journal of molecular biology},
  year={1995},
  volume={252 1},
  pages={
          102-21
        }
}
  • M. Akke, S. Forsén, W. Chazin
  • Published 1995
  • Chemistry, Medicine
  • Journal of molecular biology
  • The three-dimensional solution structure of (Cd2+)1-calbindin D9k has been determined by distance geometry, restrained molecular dynamics and relaxation matrix calculations using experimental constraints obtained from two-dimensional 1H and 15N-1H NMR spectroscopy. The final input data consisted of 1055 NOE distance constraints and 71 dihedral angle constraints, corresponding to 15 constraints per residue on average. The resulting ensemble of 24 structures has no distance or dihedral angle… CONTINUE READING
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