Solution structure and dynamics of integral membrane proteins by NMR: a case study involving the enzyme PagP.

@article{Hwang2005SolutionSA,
  title={Solution structure and dynamics of integral membrane proteins by NMR: a case study involving the enzyme PagP.},
  author={Peter M. Hwang and Lewis E. Kay},
  journal={Methods in enzymology},
  year={2005},
  volume={394},
  pages={335-50}
}
Solution NMR spectroscopy is rapidly becoming an important technique for the study of membrane protein structure and dynamics. NMR experiments on large perdeuterated proteins typically exploit the favorable relaxation properties of backbone amide (15)N-(1)H groups to obtain sequence-specific chemical shift assignments, structural restraints, and a wide range of dynamics information. These methods have proven successful in the study of the outer membrane enzyme, PagP, not only for obtaining the… CONTINUE READING

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