Solution structure and backbone dynamics of the defunct domain of calcium vector protein.

@article{Thret2001SolutionSA,
  title={Solution structure and backbone dynamics of the defunct domain of calcium vector protein.},
  author={I Th{\'e}ret and S. Baladi and Jos A. Cox and Jacques Gallay and Hiromi Sakamoto and Constantin T. Craescu},
  journal={Biochemistry},
  year={2001},
  volume={40 46},
  pages={13888-97}
}
CaVP (calcium vector protein) is a Ca(2+) sensor of the EF-hand protein family which is highly abundant in the muscle of Amphioxus. Its three-dimensional structure is not known, but according to the sequence analysis, the protein is composed of two domains, each containing a pair of EF-hand motifs. We determined recently the solution structure of the C-terminal domain (Trp81-Ser161) and characterized the large conformational and dynamic changes induced by Ca(2+) binding. In contrast, the N… CONTINUE READING