Solution-phase synthesis of a combinatorial library of 3-[4-(coumarin-3-yl)-1,3-thiazol-2-ylcarbamoyl]propanoic acid amides.

@article{Zhuravel2005SolutionphaseSO,
  title={Solution-phase synthesis of a combinatorial library of 3-[4-(coumarin-3-yl)-1,3-thiazol-2-ylcarbamoyl]propanoic acid amides.},
  author={Irina O Zhuravel and Sergiy M. Kovalenko and Sergiy V Vlasov and Valentin P Chernykh},
  journal={Molecules},
  year={2005},
  volume={10 2},
  pages={444-56}
}
The parallel solution-phase synthesis of a new combinatorial library of 3-[4-(R1-coumarin-3-yl)-1,3-thiazol-2-ylcarbamoyl]propanoic acid amides 9 has been developed. The synthesis involves two steps: 1) the synthesis of core building blocks - 3- [4-(coumarin-3-yl)-1,3-thiazol-2-ylcarbamoyl]propanoic acids, 6 - by the reaction of 3-(omega-bromacetyl)coumarins 1 with 3-amino(thioxo)methylcarbamoylpropanoic acid (5); 2) the synthesis of the corresponding 3-[4-(coumarin-3-yl)-1,3-thiazol-2-yl… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
3 Citations
6 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-6 of 6 references

Kazan

  • S. N. Kovalenko, V. P. Chernykh, +4 authors A. V. Silin
  • Med . Zh .
  • 1995

Azerb

  • A. L. Mndzhoyan, M. A. Kaldrikyan, R. G. Melik-Ogandzhanyan, A. A. Aroyan
  • Khim . Zh .
  • 1967

Kaldrikyan, M.A.; Melik-Ogandzhanyan, R.G.; Aroyan

  • A. L. Mndzhoyan
  • A.A. Azerb. Khim. Zh. 1967,
  • 1967

Izv. АN Armyan

  • A. L. Mndzhoyan, V. G. Afrikyan
  • SSR Ser. Khim. Nauk 1957,
  • 1957
2 Excerpts

Docl

  • Hui-Ling, A. L. Mndzhoyan, A. A. Grigoryan
  • А N А rmyan . SSR
  • 1956

Docl. АN Аrmyan

  • A. L. Mndzhoyan, A. A. Grigoryan
  • SSR 1956,
  • 1956
1 Excerpt

Similar Papers

Loading similar papers…