Solution-mediated crystallization of amorphous azithromycin.

Abstract

Water and water vapor are the bane of amorphous drug stability, both in storage and after administration. As is to be expected, crystallization of amorphous azithromycin did occur when exposed to water as dissolution medium. However, experimental results showed that, although solution-mediated phase transformation had occurred, it was not a rapid process… (More)
DOI: 10.1691/ph.2017.7035

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