Solution behaviour of myo-inositol hexakisphosphate in the presence of multivalent cations. Prediction of a neutral pentamagnesium species under cytosolic/nuclear conditions.

@article{Torres2005SolutionBO,
  title={Solution behaviour of myo-inositol hexakisphosphate in the presence of multivalent cations. Prediction of a neutral pentamagnesium species under cytosolic/nuclear conditions.},
  author={Julia Ara{\'u}jo Torres and Sixto Dom{\'i}nguez and Mar{\'i}a Fernanda Cerd{\'a} and Gonzalo Obal and A. C. Mart{\'i}n Mederos and Robin F. Irvine and Alvaro Diaz and Carlos Kremer},
  journal={Journal of inorganic biochemistry},
  year={2005},
  volume={99 3},
  pages={
          828-40
        }
}
myo-Inositol hexakisphosphate (InsP6) is an ubiquitous and abundant molecule in the cytosol and nucleus of eukaryotic cells whose biological functions are incompletely known. A major hurdle for studying the biology of InsP6 has been a deficiency of a full understanding of the chemistry of its interaction with divalent and trivalent cations. This deficiency has limited our appreciation of how it remains in solution within cells, and the likely degree to which it might interact in vivo with… CONTINUE READING
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