Solution Dependence of the Collisional Activation of Ubiquitin [M + 7H]7+ Ions

@article{Shi2014SolutionDO,
  title={Solution Dependence of the Collisional Activation of Ubiquitin [M + 7H]7+ Ions},
  author={Huilin Shi and Natalya Atlasevich and Samuel I. Merenbloom and David E. Clemmer},
  journal={Journal of The American Society for Mass Spectrometry},
  year={2014},
  volume={25},
  pages={2000-2008}
}
AbstractThe solution dependence of gas-phase unfolding for ubiquitin [M + 7H]7+ ions has been studied by ion mobility spectrometry-mass spectrometry (IMS-MS). Different acidic water:methanol solutions are used to favor the native (N), more helical (A), or unfolded (U) solution states of ubiquitin. Unfolding of gas-phase ubiquitin ions is achieved by collisional heating and newly formed structures are examined by IMS. With an activation voltage of 100 V, a selected distribution of compact… CONTINUE READING

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