Solute transport in the deep and calcified zones of articular cartilage.

  title={Solute transport in the deep and calcified zones of articular cartilage.},
  author={Kenton Arkill and C. P. Winlove},
  journal={Osteoarthritis and cartilage},
  volume={16 6},
OBJECTIVES (1) To establish whether the tidemark and calcified cartilage are permeable to low molecular weight solutes, thereby providing a potential pathway for nutrition of cells in the deep cartilage. (2) To investigate transport from the subchondral microcirculation into calcified cartilage in an intact perfused joint and the effects on transport of static loading. METHODS The permeability of the tidemark and calcified cartilage was investigated in plugs of cartilage and subchondral bone… CONTINUE READING


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