Soluble urokinase receptor is elevated in cerebrospinal fluid from patients with purulent meningitis and is associated with fatal outcome.

@article{Ostergaard2004SolubleUR,
  title={Soluble urokinase receptor is elevated in cerebrospinal fluid from patients with purulent meningitis and is associated with fatal outcome.},
  author={Christian Ostergaard and Thomas Benfield and Jens D. Lundgren and Jesper Eugen-Olsen},
  journal={Scandinavian journal of infectious diseases},
  year={2004},
  volume={36 1},
  pages={14-9}
}
The urokinase-type plasminogen activator system has been suggested to play a pathophysiological role in brain damage. The aim of this study was to evaluate CSF levels of suPAR in 183 patients clinically suspected of having meningitis on admission. Of these, 54 patients were found to have purulent meningitis, 63 had lymphocytic meningitis, 12 had encephalitis, and 54 patients were suspected of, but had no evidence of, meningitis. There was a significant difference in suPAR levels among patient… CONTINUE READING