Soluble tumor necrosis factor receptors shed by breast tumor cells inhibit macrophage chemotaxis.

Abstract

Breast tumor cells alter their microenvironment in part through the expression of protumor molecules that influence macrophages during tumor progression and metastasis. Macrophage recruitment is stimulated by chemotactic factors, including tumor necrosis factor alpha (TNF-α), which also stimulates the cytotoxic/tumor cell killing macrophage phenotype… (More)
DOI: 10.1089/jir.2013.0009

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