Soluble serum Klotho in diabetic nephropathy: relationship to VEGF-A.

@article{Kacs2012SolubleSK,
  title={Soluble serum Klotho in diabetic nephropathy: relationship to VEGF-A.},
  author={Ina Maria Kacs{\'o} and Cosmina I Bondor and Gabriel Kacso},
  journal={Clinical biochemistry},
  year={2012},
  volume={45 16-17},
  pages={1415-20}
}
OBJECTIVES Both kidney expression and soluble serum Klotho are influenced by chronic kidney disease (CKD) and diabetes. Serum Klotho is a yet poorly explored biomarker. We describe, for the first time to our knowledge, serum Klotho in diabetic patients with CKD and its relationship to vascular endothelial growth factor A (VEGF-A). DESIGN AND METHODS We included 43 controls and 146 diabetic patients with different stages of CKD. Laboratory evaluation, urinary albumin/creatinine ratio (UACR… CONTINUE READING
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