Soluble recombinant HTLV-1 surface glycoprotein competitively inhibits syncytia formation and viral infection of cells.

Abstract

Efficient entry into, and infection of, human cells by human T-cell leukaemia virus type-1 (HTLV-1) is mediated by the viral envelope glycoproteins, gp46 and gp21. The gp46 surface glycoprotein binds to an as yet unidentified cell surface receptor, thereby, allowing the gp21 transmembrane glycoprotein to initiate fusion of the viral and cellular membranes… (More)

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@article{Jassal2001SolubleRH, title={Soluble recombinant HTLV-1 surface glycoprotein competitively inhibits syncytia formation and viral infection of cells.}, author={Surita Jassal and Michael D. Lairmore and Anne Leigh-Brown and David W. Brighty}, journal={Virus research}, year={2001}, volume={78 1-2}, pages={17-34} }