Soluble receptor activator of nuclear factor-kappa B ligand and risk for cardiovascular disease.

Abstract

BACKGROUND Overexpression of receptor activator of nuclear factor-kappaB ligand (RANKL) is a prominent feature of vulnerable atherosclerotic lesions prone to rupture and was thought to contribute to the transition from a stable to an unstable plaque phenotype in both human and murine atherosclerosis because of its ability to promote matrix degradation… (More)

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