Soluble guanylate cyclase: the forgotten sibling.

  title={Soluble guanylate cyclase: the forgotten sibling.},
  author={Adrian J Hobbs},
  journal={Trends in pharmacological sciences},
  volume={18 12},
Despite widespread distribution in most mammalian cells, the role of soluble guanylate cyclase has, until recently, been poorly defined, especially when compared with its more illustrious sibling, adenylate cyclase. In this review Adrian Hobbs outlines some of the reasons why the soluble guanylate cyclase-cGMP pathway has remained outside the signalling… CONTINUE READING