Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response.

Abstract

T cell Ig mucin 3 (Tim-3) has been found to play an important role in Th1-mediated auto- and alloimmune responses, but the function of soluble form of Tim-3 (sTim-3) remains to be elucidated. In this study, we report the inhibitory effect of sTim-3 on T cell-mediated immune response. In this study, sTim-3 mRNA was found, among different tissues and organs… (More)

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@article{Geng2006SolubleFO, title={Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response.}, author={Hui Geng and Gui-mei Zhang and Dong Li and Hui Zhang and Ye Yuan and Han-gang Zhu and Han Xiao and Ling-fei Han and Zuo-hua Feng}, journal={Journal of immunology}, year={2006}, volume={176 3}, pages={1411-20} }