Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells.

@article{Urbich2005SolubleFR,
  title={Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells.},
  author={Carmen Urbich and Alexandra Aicher and Christopher Heeschen and Elisabeth Dernbach and Wolf K. Hofmann and Andreas Michael Zeiher and Stefanie Dimmeler},
  journal={Journal of molecular and cellular cardiology},
  year={2005},
  volume={39 5},
  pages={
          733-42
        }
}
Circulating endothelial progenitor cells (EPC) are incorporated into newly formed capillaries, enhance neovascularization after hind limb ischemia and improve cardiac function after ischemic injury. Incorporated progenitor cells may also promote neovascularization and cardiac regeneration by releasing factors, which act in a paracrine manner to support local angiogenesis and mobilize tissue residing progenitor cells. Therefore, we analyzed the expression profile of cytokines in human peripheral… CONTINUE READING
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