Soluble epoxide hydrolase deficiency ameliorates acute pancreatitis in mice.


Acute pancreatitis (AP) is a frequent gastrointestinal disorder that causes significant morbidity and its incidence has been progressively increasing. AP starts as a local inflammation in the pancreas that often leads to systemic inflammatory response and complications. Soluble epoxide hydrolase (sEH) is a cytosolic enzyme whose inhibition in murine models… (More)
DOI: 10.1016/j.freeradbiomed.2014.10.766