Soluble dietary fiber protects against cholesterol gallstone formation.

@article{Schwesinger1999SolubleDF,
  title={Soluble dietary fiber protects against cholesterol gallstone formation.},
  author={Wayne H. Schwesinger and William E. Kurtin and C. P. Page and Ronald M. Stewart and R. Johnson},
  journal={American journal of surgery},
  year={1999},
  volume={177 4},
  pages={
          307-10
        }
}
Dietary fenugreek and onion attenuate cholesterol gallstone formation in lithogenic diet–fed mice
TLDR
The antilithogenic influence was highest with fenugreek alone, and the presence of onion along with it did not further increase this effect, and there was also no additive effect of the two spices in the recovery of antioxidant molecules or in the antioxidant enzyme activities.
Dietary fenugreek seed regresses preestablished cholesterol gallstones in mice.
TLDR
Evidence is provided of the potency of hypolipidemic fenugreek seeds in regressing preestablished CGS, and this beneficial antilithogenic effect is attributable to its primary influence on cholesterol levels.
Anti-cholelithogenic effect of dietary tender cluster beans (Cyamopsis tetragonoloba) on the formation of cholesterol gallstones in mice.
TLDR
Dietary tender cluster beans exerted an anti-cholelithogenic influence by decreasing cholesterol hypersecretion into bile and, hence, the cholesterol saturation index, decreasing the formation of lithogenic bile in experimental mice.
Variations in Dietary Intake Between Newly Diagnosed Gallstone Patients and Controls
TLDR
Dietary interventions that emphasize the prevention effect of some nutrients and the contributory effect of others might provide a method of avoiding the formation of gallstones.
Diet as a Risk Factor for Cholesterol Gallstone Disease
TLDR
Several studies that have evaluated the role of diet as a potential risk factor for gallstone formation say that consumption of simple sugars and saturated fat has been mostly associated to a higher risk, while fiber intake and moderate consumption of alcohol, consistently reduce the risk.
Long-Term Intake of Dietary Fiber and Decreased Risk of Cholecystectomy in Women
TLDR
Increased long-term consumption of dietary fiber, particularly insoluble fiber, can reduce risk of cholecystectomy in women, and soluble fiber was significantly associated with a reduced risk.
Frequent nut consumption and decreased risk of cholecystectomy in women.
TLDR
In women, frequent nut consumption is associated with a reduced risk of cholecystectomy, and in analyses examining consumption of peanuts and other nuts separately, both wereassociated with a lower risk of CholecyStectomy.
A prospective cohort study of nut consumption and the risk of gallstone disease in men.
TLDR
It is suggested that frequent nut consumption is associated with a reduced risk of gallstone disease in men after adjustment for age and other known or suspected risk factors.
Gallstones: Environment, Lifestyle and Genes
TLDR
The spectrum of environmental and genetic risk factors which should pave the way to ‘personalised’ strategies for the prevention and therapy of gallstones are summarized.
Obesity and Gallstones
TLDR
Excess body weight represents the main cause for the development of GD; nevertheless, there have been described multiple risk factors for its development, among them modifiable risk factors as diet, lifestyle, physical inactivity, and non-modifiable risk Factors as ethnicity, female sex, advanced age, parity, and genetic mutations.
...
...

References

SHOWING 1-10 OF 38 REFERENCES
Alcohol Protects Against Cholesterol Gallstone Formation
TLDR
It is confirmed that ethanol inhibits cholesterol gallstone formation and it is suggested that this effect is dependent on reductions of biliary cholesterol and selective changes in bile acid concentrations.
Effects of psyllium hydrophilic mucilloid on LDL-cholesterol and bile acid synthesis in hypercholesterolemic men.
TLDR
The goal of the current study was to determine the mechanism of the hypocholesterolemic effect of psyllium using a randomized, double-blind, crossover design and it is concluded that Psyllium lowers LDL cholesterol primarily via stimulation of bile acid synthesis.
The effect of wheat bran upon bile salt metabolism and upon the lipid composition of bile in gallstone patients
TLDR
Bran probably operates primarily on the colon, reducing the formation or absorption of the bacterial metabolite DC, a substance which impairs CDC synthesis, and the size of the bile salt pool did not change.
[Effects of fiber administration in the prevention of gallstones in obese patients on a reducing diet. A clinical trial].
TLDR
A beneficial effect of a rational diet with fiber supplementation to prevent GD development in obese patients included in a weight reduction program is suggested.
Additive hypocholesterolemic effect of psyllium and cholestyramine in the hamster: influence on fecal sterol and bile acid profiles.
TLDR
It is concluded that, while both agents lower cholesterol by a mechanism of increased bile acid excretion, psyllium does not bind bile acids in vivo and lend further support for the concomitant use of these agents for cholesterol-lowering.
Cholesterol-lowering effects of psyllium-enriched cereal as an adjunct to a prudent diet in the treatment of mild to moderate hypercholesterolemia.
TLDR
Adding psyllium-enriched cereal to a prudent low-fat diet may enhance dietary management of hypercholesterolemia, and serum cholesterol and low-density lipoprotein concentrations were significantly lower on Psyllium than on wheat-bran cereal.
Effects of ursodeoxycholic acid and aspirin on the formation of lithogenic bile and gallstones during loss of weight.
TLDR
It is concluded that ursodeoxycholic acid prevents lithogenic changes in bile and the formation of gallstones in obese subjects during loss of weight.
Cholesterol 7 alpha-hydroxylase activity is increased by dietary modification with psyllium hydrocolloid, pectin, cholesterol and cholestyramine in rats.
TLDR
Data support the hypothesis that the hypocholesterolemic effect of soluble fibers is modulated through increased synthesis and therefore pool size of bile acids.
Effect on blood lipids of very high intakes of fiber in diets low in saturated fat and cholesterol.
TLDR
Very high intakes of foods rich in soluble fiber lower blood cholesterol levels even when the main dietary modifiers of blood lipids--namely, saturated fat and cholesterol--are greatly reduced.
...
...