Soluble and cleaved forms of the urokinase-receptor: degradation products or active molecules?

@article{Montuori2005SolubleAC,
  title={Soluble and cleaved forms of the urokinase-receptor: degradation products or active molecules?},
  author={Nunzia Montuori and V Visconte and Guido Rossi and Pia Ragno},
  journal={Thrombosis and haemostasis},
  year={2005},
  volume={93 2},
  pages={192-8}
}
The urokinase-mediated plasminogen activation (PA) system is involved in many physiological and pathological events that include cell migration and tissue remodelling, such as embryogenesis, ovulation, inflammation, wound healing, angiogenesis, and tumor invasion and metastasis. The urokinase receptor (uPAR) is a key molecule of this system and can bind extracellular and cell membrane molecules such as urokinase (uPA), vitronectin (VN), integrins and chemotaxis receptors. These multiple… CONTINUE READING

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Cellsurface acceleration of urokinase-catalyzed receptor cleavage

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Highly Influential
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