Soluble ST2 predicts outcome and hemorrhagic transformation after acute stroke

@inproceedings{Wolcott2017SolubleSP,
  title={Soluble ST2 predicts outcome and hemorrhagic transformation after acute stroke},
  author={Zoe Wolcott and Ayush Batra and Matthew B Bevers and Cristina Sastre and Jane C. Khoury and Matthew I Sperling and Brett C Meyer and Kyle B Walsh and Opeolu Adeoye and J P Broderick and W T Kimberly},
  booktitle={Annals of clinical and translational neurology},
  year={2017}
}
OBJECTIVE ST2 is a member of the toll-like receptor superfamily that can alter inflammatory signaling of helper T-cells. We investigated whether soluble ST2 (sST2) could independently predict outcome and hemorrhagic transformation (HT) in the setting of stroke. METHODS We measured sST2 in patients enrolled in the Specialized Program of Translational Research in Acute Stroke (SPOTRIAS) network biomarker study. 646 patients had plasma samples collected at the time of hospital admission and 210… CONTINUE READING

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