Soluble ST2 is associated with adverse outcome in patients with heart failure of ischaemic aetiology.

@article{Broch2012SolubleSI,
  title={Soluble ST2 is associated with adverse outcome in patients with heart failure of ischaemic aetiology.},
  author={Kaspar Broch and Thor Ueland and St{\aa}le Haugset Nymo and John Kjekshus Kjekshus and Johannes Hulthe and Pieter Muntendam and John J V McMurray and John Wikstrand and John George Franklin Cleland and P. A. Aukrust and Lars Gullestad},
  journal={European journal of heart failure},
  year={2012},
  volume={14 3},
  pages={
          268-77
        }
}
AIMS In patients with ischaemic heart failure (HF), myocardial dysfunction often progresses. Elevated levels of soluble ST2 (sST2) are associated with a poor prognosis, but an association between sST2 and worsening heart failure per se has not been established. We assessed the association between sST2 and cause-specific outcome in 1449 patients enrolled in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA study). METHODS AND RESULTS Soluble ST2 was measured with a… CONTINUE READING
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