Soluble ST2 Plasma Concentrations Predict Mortality in HBV-Related Acute-on-Chronic Liver Failure

@inproceedings{Lei2015SolubleSP,
  title={Soluble ST2 Plasma Concentrations Predict Mortality in HBV-Related Acute-on-Chronic Liver Failure},
  author={Ziying Lei and Zhishuo Mo and Jianyun Zhu and Xiuqing Pang and Xingrong Zheng and Zhebin Wu and Ke Wang and Xinhua Li and Dongying Xie and Zhi-Liang Gao},
  booktitle={Mediators of inflammation},
  year={2015}
}
Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is a rapidly progressing and frequently fatal condition. The aim of this study was to determine whether interleukin- (IL-) 33 and soluble ST2 (sST2) were associated with disease severity and mortality in HBV-ACLF. We found that plasma levels of sST2 but not IL-33 were higher in HBV-ACLF patients compared with chronic hepatitis B (CHB) patients and healthy controls. However, plasma levels of IL-33, TNF-α, IFN-γ, and IL-10 did… CONTINUE READING
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