Soluble Nogo-A in CSF is not a useful biomarker for multiple sclerosis.

@article{Lindsey2008SolubleNI,
  title={Soluble Nogo-A in CSF is not a useful biomarker for multiple sclerosis.},
  author={J. William Lindsey and Michael P. Crawford and Landon M Hatfield},
  journal={Neurology},
  year={2008},
  volume={71 1},
  pages={35-7}
}
OBJECTIVE To determine whether the presence of Nogo-A protein in CSF is a useful biomarker for multiple sclerosis (MS). METHODS We performed Western blots on CSF from patients with MS and controls with the commercially available Nogo-A antibody and secondary antibody used in a prior report. We used densitometry to measure band density on Western blot. Controls included blots without primary antibody, samples without dithiothreitol (DTT), CSF passed through a protein G column, and Western… CONTINUE READING