Soluble L-selectin is present in human plasma at high levels and retains functional activity

Abstract

L-selectin expressed by granulocytes, lymphocytes, and monocytes is responsible for initial leukocyte attachment to inflamed endothelium and high endothelial venules of peripheral lymph nodes. After leukocyte activation in vitro, L-selectin is rapidly shed from the cell surface. In this study, shed L-selectin (sL-selectin) from both lymphocytes and… (More)

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@article{Schleiffenbaum1992SolubleLI, title={Soluble L-selectin is present in human plasma at high levels and retains functional activity}, author={Boris Eugen Schleiffenbaum and Olivier Spertini and Thomas F. Tedder}, journal={The Journal of Cell Biology}, year={1992}, volume={119}, pages={229 - 238} }