Soluble Klotho is not independently associated with cardiovascular disease in a population of dialysis patients

@inproceedings{Buiten2014SolubleKI,
  title={Soluble Klotho is not independently associated with cardiovascular disease in a population of dialysis patients},
  author={Maurits S. Buiten and Mih{\'a}ly K. de Bie and Annet Bouma-de Krijger and Bastiaan van Dam and Friedo Wilhelm Dekker and J Wouter Jukema and Ton J Rabelink and Joris I. Rotmans},
  booktitle={BMC nephrology},
  year={2014}
}
BACKGROUND Dialysis patients suffer from a high burden of cardiovascular disease (CVD). Partly this is due to progressive deterioration of calcium-phosphate homeostasis. Previous studies suggested that besides FGF-23, low levels of Klotho, a protein linked to aging, might constitute a key factor in this detrimental relationship. The purpose of the present study was to determine the relationship between serum Klotho (sKlotho) and the presence of CVD in dialysis patients. METHODS Plasma levels… CONTINUE READING