Soluble HTLV-I Tax1 protein stimulates proliferation of human peripheral blood lymphocytes.

@article{Marriott1991SolubleHT,
  title={Soluble HTLV-I Tax1 protein stimulates proliferation of human peripheral blood lymphocytes.},
  author={Susan J. Marriott and P F Lindholm and Robert L. Reid and John N. Brady},
  journal={The New biologist},
  year={1991},
  volume={3 7},
  pages={678-86}
}
Human T-cell leukemia virus type I (HTLV-I) is associated with two human diseases, adult T-cell leukemia (ATL) and tropical spastic paraparesis/HTLV-I associated myelopathy (TSP/HAM). Lymphocytes from patients with ATL or TSP/HAM display abnormal proliferation properties in culture. Here we report that purified, soluble Tax1 protein can be taken up by, and… CONTINUE READING