Soluble HLA-DR molecules in patients with HLA class II versus class I associated disorders.

@article{Weyand1991SolubleHM,
  title={Soluble HLA-DR molecules in patients with HLA class II versus class I associated disorders.},
  author={Cornelia M Weyand and M C Jendro and J{\"o}rg J Goronzy},
  journal={Autoimmunity},
  year={1991},
  volume={8 4},
  pages={
          281-7
        }
}
  • Cornelia M Weyand, M C Jendro, Jörg J Goronzy
  • Published in Autoimmunity 1991
  • Medicine
  • HLA genes have been identified as key genetic factors contributing to many chronic diseases characterized by autoimmune features. The role of HLA encoded molecules in the pathogenesis of these diseases is unresolved. We have now analysed soluble HLA-DR molecules circulating in the serum of patients with different autoimmune diseases and have defined parameters controlling serum levels. Patients with HLA-DR associated diseases were characterized by elevated serum concentrations of HLA-DR… CONTINUE READING

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