Soluble HLA-DR levels in the maternal circulation of normal and pathologic pregnancy.

  title={Soluble HLA-DR levels in the maternal circulation of normal and pathologic pregnancy.},
  author={Andrea Steinborn and Vera Rebmann and Alexander Scharf and Christof Sohn and Hans Grosse-Wilde},
  journal={American journal of obstetrics and gynecology},
  volume={188 2},
OBJECTIVE The purpose of this study was to determine that circulating HLA-DR molecules are important candidates for the monitoring of maternal immunostimulation and immunosuppression. STUDY DESIGN Concentrations of soluble HLA-DR molecules were estimated in EDTA plasma samples of 61 nonpregnant women, 123 healthy pregnant women in the second trimester, 66 healthy women who were delivered at term, and 136 women who were delivered because of complications such as uncontrollable preterm… CONTINUE READING


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