Soluble Glycoprotein 130 and Heat Shock Protein 27 as Novel Candidate Biomarkers of Chronic Heart Failure with Preserved Ejection Fraction.

@article{Liu2016SolubleG1,
  title={Soluble Glycoprotein 130 and Heat Shock Protein 27 as Novel Candidate Biomarkers of Chronic Heart Failure with Preserved Ejection Fraction.},
  author={Shengchen Liu and Reinard Iskandar and Wen Chen and Jie Zhang and Yifei Wang and Xin Chen and Fei Xiang},
  journal={Heart, lung & circulation},
  year={2016},
  volume={25 10},
  pages={1000-6}
}
BACKGROUND Despite their importance, the current clinical biomarkers of chronic heart failure have limitations. In this study, soluble glycoprotein 130 (sgp130), heat shock protein 27 (hsp27), dipeptidyl peptidase IV (dpp4) and cathepsin S (CTSS) were tested for their potential as novel biomarkers for diagnosing chronic heart failure (CHF) with preserved ejection fraction. METHODS We compared the circulating levels of sgp130, hsp27, dpp4, and cathepsin S in patients with CHF with preserved… CONTINUE READING