Soluble Fas (APO-1, CD95) and soluble Fas ligand in rheumatic diseases.

  title={Soluble Fas (APO-1, CD95) and soluble Fas ligand in rheumatic diseases.},
  author={Kazuhisa Nozawa and Nobuhiko Kayagaki and Yoshiaki Tokano and H. Yagita and Ko Okumura and Hiromi Hasimoto},
  journal={Arthritis and rheumatism},
  volume={40 6},
OBJECTIVE To assess levels of soluble Fas (sFas) and soluble Fas ligand (sFas-L) in sera from patients with various rheumatic diseases: systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc), polymyositis/dermatomyositis (PM/DM), mixed connective tissue disease (MCTD), and Sjogren's syndrome (SS). METHODS Levels of sFas and sFas-L were determined by a sandwich enzyme-linked immunosorbent assay. RESULTS In SLE, PM/DM, MCTD, and SS, sFas levels were… CONTINUE READING
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