Soluble Antiapoptotic Molecules and Immune Activation in Chronic Heart Failure and Unstable Angina Pectoris

@article{Fiorina2000SolubleAM,
  title={Soluble Antiapoptotic Molecules and Immune Activation in Chronic Heart Failure and Unstable Angina Pectoris},
  author={Paolo Fiorina and Ettore Astorri and Roberto Albertini and Antonio Secchi and A M Mello and Mario Lanfredini and Angelo Craveri and Giorgio Olivetti and Federico Quaini},
  journal={Journal of Clinical Immunology},
  year={2000},
  volume={20},
  pages={101-106}
}
Programmed myocyte cell death and activation of the immune system have been shown to occur in patients with congestive heart failure. Besides, unstable angina episodes are likely to be associated with immune activation. Our aim was to evaluate the role of changes in circulating levels of soluble Fas (sFas), suggestive of an enhanced inhibitory response to ongoing apoptosis, and soluble IL2 receptor (sIL2-R), indicative of T-lymphocyte activation, in chronic heart failure and unstable angina… CONTINUE READING

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