Soluble Aminopeptidase N / CD 13 in Malignant and Nonmalignant Effusions and Intratumoral Fluid 1


Purpose: On the basis of the finding of marked overexpression in angiogenic microvessels, aminopeptidase N/CD13 has recently been suggested to play a prominent role in tumor angiogenesis. A soluble form of CD13 (sCD13) is present in human plasma, but its role in cancer has not been addressed. We hypothesized that sCD13 would be shed by tumor cells and/or… (More)

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