Solubilization of menthol by platycodin D in aqueous solution: an integrated study of classical experiments and dissipative particle dynamics simulation.

  title={Solubilization of menthol by platycodin D in aqueous solution: an integrated study of classical experiments and dissipative particle dynamics simulation.},
  author={Haiou Ding and Qianqian Yin and Guang Wan and Xingxing Dai and Xinyuan Shi and Yanjiang Qiao},
  journal={International journal of pharmaceutics},
  volume={480 1-2},
Menthol (M) and platycodin D (PD) are the main active ingredients in Mentha haplocalyx and Platycodon grandiflorum A. DC., respectively. They are commonly used in combination in traditional Chinese medicine. In this study, laboratory experiments and computer simulations were used to investigate the solubilization of M by PD, which was believed to be one of the main causes of the synergistic effect of M. haplocalyx and P. grandiflorum A. DC. Results showed that both the method by which M was… 
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  • Y. Ma
  • Biology
    Applied Ecology and Environmental Research
  • 2019
Platycodon grandiflorum has a wide range of adaptability to light intensity, and can not only utilize intense light efficiently, but also has shade tolerance.


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