Solubility prediction for furosemide in water-cosolvent mixtures using the minimum number of experiments.

Abstract

The mole fraction solubility of a poorly water soluble loop diuretic, furosemide, was determined in aqueous binary mixtures of ethanol, propylene glycol, and glycerol from 0% to 100% cosolvent concentrations at 25 degrees C. Solubility predictions based on the minimum number of experimental data points were performed using the commonly used accurate… (More)

Topics

Cite this paper

@article{JouybanGharamaleki2001SolubilityPF, title={Solubility prediction for furosemide in water-cosolvent mixtures using the minimum number of experiments.}, author={A Jouyban-Gharamaleki and Siavash Dastmalchi and H. K. Chan and Jalal Hanaee and A. Javanmard and Mohammad Barzegar-Jalali}, journal={Drug development and industrial pharmacy}, year={2001}, volume={27 6}, pages={577-83} }