Hepatic solitary necrotic nodule (SNN) is an unusual, benign mass forming lesion, first described by Shepherd and Lee in 1983. Since then, some possible pathogenetic hypotheses have been suggested. However, its exact etiology is still not established and disease entity of hepatic SNN remains uncertain. Although most SNNs show benign clinical course, it is difficult to distinguish from other lesions, including hepatic tumors and cancer metastasis by clinically and radiologically. In this issue, we present a case of SNN in a 48-year-old woman and discuss the histologic findings.