Solid-state properties and crystal structure of gliclazide.

  title={Solid-state properties and crystal structure of gliclazide.},
  author={Catherine Winters and Leonard Shields and Peter Timmins and Peter York},
  journal={Journal of pharmaceutical sciences},
  volume={83 3},
The solid-state characterization of gliclazide, for which no analytical standard was previously available, has been completed by extensive structural and physical analytical examination. The crystal and molecular structure for gliclazide was determined by single-crystal X-ray diffraction. Gliclazide crystallizes in the monoclinic space group P2(1)/n, with the unit cell dimensions a = 10.828(2) A, b = 14.342(19) A, c = 11.005(6) A, and with beta = 106.97(2) degrees, V = 1635(12) A3, and Z = 4… CONTINUE READING