Solid state and dissolution rate characterization of co-ground mixtures of nifedipine and hydrophilic carriers.

@article{Friedrich2005SolidSA,
  title={Solid state and dissolution rate characterization of co-ground mixtures of nifedipine and hydrophilic carriers.},
  author={Heike Friedrich and Aly H. Nada and Roland A Bodmeier},
  journal={Drug development and industrial pharmacy},
  year={2005},
  volume={31 8},
  pages={719-28}
}
Co-ground powders of the poorly water-soluble drug nifedipine and a hydrophilic carrier, [partially hydrolyzed gelatin (PHG), polyvinylpyrrolidone (PVP), sodium dodecyl sulfate (SDS), hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG), urea or Pluronic F108] were prepared in order to improve the dissolution rate of nifedipine. The effects of… CONTINUE READING