Solid-phase supports for oligonucleotide synthesis.

  title={Solid-phase supports for oligonucleotide synthesis.},
  author={Andrei P Guzaev},
  journal={Current protocols in nucleic acid chemistry},
  volume={Chapter 3},
This unit attempts to provide a reasonably complete inventory of over 280 solid supports available to oligonucleotide chemists for preparation of natural and 3'-modified oligonucleotides. Emphasis is placed on non-nucleosidic solid supports. The relationship between the structural features of linkers and their behavior in oligonucleotide synthesis and… CONTINUE READING