Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery.

@article{Martn2012SolidphaseassistedSO,
  title={Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery.},
  author={Irene Mart{\'i}n and Christian Dohmen and Carlos Mas-Moruno and Christina Troiber and Petra Kos and David Schaffert and Ulrich L{\"a}chelt and Meritxell Teixid{\'o} and Michael Guenther and Horst Kessler and Ernest Giralt and Ernst Wagner},
  journal={Organic & biomolecular chemistry},
  year={2012},
  volume={10 16},
  pages={3258-68}
}
In the forthcoming era of cancer gene therapy, efforts will be devoted to the development of new efficient and non-toxic gene delivery vectors. In this regard, the use of Fmoc/Boc-protected oligo(ethane amino)acids as building blocks for solid-phase-supported assembly represents a novel promising approach towards fully controlled syntheses of effective gene… CONTINUE READING