Solid lipid nanoparticles for parenteral drug delivery.

@article{Wissing2004SolidLN,
  title={Solid lipid nanoparticles for parenteral drug delivery.},
  author={Sylvia A. Wissing and Oliver Kayser and Rainer Helmut M{\"u}ller},
  journal={Advanced drug delivery reviews},
  year={2004},
  volume={56 9},
  pages={
          1257-72
        }
}
This review describes the use of nanoparticles based on solid lipids for the parenteral application of drugs. Firstly, different types of nanoparticles based on solid lipids such as "solid lipid nanoparticles" (SLN), "nanostructured lipid carriers" (NLC) and "lipid drug conjugate" (LDC) nanoparticles are introduced and structural differences are pointed out. Different production methods including the suitability for large scale production are described. Stability issues and drug incorporation… CONTINUE READING
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